Like most technical endeavors, sending email is a lot harder than it  looks! The simple solutions that are entirely adequate when you have to  send a couple of dozen daily emails simply don't work when you need to  send out hundreds, thousands, or even millions of emails over the same  time period.
To pick just one issue, let's talk about something that the email pros call deliverability.  This is a measure of how well you are doing at actually getting email  through to the intended recipients. It is affected by a number of  factors and is absolutely crucial to the successful implementation of  your email strategy. In order to maximize deliverability, you need to  work with multiple Internet Service Providers (ISPs) to ensure that they  trust your content, and you need to monitor and control the number of  complaints and bounces that you generate. After spending time and money  building out an internal hardware platform, negotiating expensive  agreements with third-party vendors, learning the ins and outs of SMTP,  and becoming familiar with (not to mention gaining control of) all of  the factors that affect deliverability, you may find yourself wondering  why you wanted to send email in the first place. Amazon's Chris Wheeler  (Technical Program Manager for Amazon SES and an  industry recognized  deliverability expert), told me "You must get your  house in order  before sending your first piece of mail. Otherwise, your  mail will end  up in the spam folder, may not be delivered at all, or you may be  blocked from sending any more mail."
 The new Amazon Simple Email Service  (SES) will make it easy for you to send email with minimal setup and  maximum scalability. Amazon SES is based on the scalable technology used  by Amazon sites around the world to send billions of messages a year.
 The new Amazon Simple Email Service  (SES) will make it easy for you to send email with minimal setup and  maximum scalability. Amazon SES is based on the scalable technology used  by Amazon sites around the world to send billions of messages a year.You'll be able to send email without having to worry about the  undifferentiated heavy lifting of infrastructure management, configuring  your hosts for optimal sending, and the like. Amazon SES also provides  you with access to a number of metrics that will provide you with the  feedback needed to tune your email strategy to maximize deliverability.
When you first register, you'll have access to the SES "sandbox"  where you can send email only to addresses that you have verified. The  verification process sends a confirmation email to the address to be  verified; the recipient must click on a link embedded in the email in  order to verify the address. You must also verify the email address (or  addresses) that will be used to send messages. At this point, with  verified addresses in hand, you can send up to 200 messages per day, at a  maximum rate of 1 message per second. These limits will allow you to  develop and test your application. This address verification process is  intended to allow you to develop and debug your application in a  controlled environment. It will also help to maintain your reputation as  a sender of high quality email.
Once your application is up and running, the next step is to request production access using the SES Production Access Request Form.  We'll review your request and generally contact you within 24 hours.  Once granted production access, you will no longer have to verify the  destination addresses and you'll be able to send email to any address.  SES will begin to increase your daily sending quota and your maximum  send rate based on a number of factors including the amount of email  that you send, the number of rejections and bounces that occur, and the  number of complaints that it generates. This will occur gradually over  time as your activities provide evidence that you are using SES in a  responsible manner. The combination of sandbox access, production  access, and the gradual increase in quotas will allow us to help ensure  high deliverability for all customers of SES. This is exactly the same  process that bulk senders of email, including Amazon.com, use to  “season” their sending channels.
Newly verified production accounts can send up to 1,000 emails every  24 hours. The SES team has told me that, while it might vary over time,  with responsible use this quota currently can grow to 10,000 daily  messages within 3 days and up to 1,000,000 daily messages within a  couple of weeks. Similarly, the maximum send rate will start out at 1  email per second, and can rise to 10 per second within 3 days, and all  the way to 90 per second within a couple of weeks. These increases are  based on usage, and occur automatically as you start to approach your  existing limits. You can contact us if you need to send more than  1,000,000 emails per day or at a rate in excess of 90 per second and  we'll do our best to accommodate you.
The Simple Email Service  will provide you with performance data on  your email so that you can  track your status and adjust your email  sending model if necessary. SES  will also provide you with valuable  feedback from ISPs in the form of  complaints from email recipients.
You can use SES by calling the SES APIs or from the command line. You  can also configure your current Mail Transfer Agent to route your email  through SES using the directions contained in the SES Developer Guide.
 The SES APIs are pretty simple:
- You use VerifyEmailAddress, ListVerifiedEmailAddresses, and DeleteVerifiedEmailAddress to manage the list of verified email addresses associated with your account.
- You use SendEmail to send properly formatted emails (supplying From, To, Subject and a message body) and SendRawEmail to manually compose and send more sophisticated emails which include additional headers or MIME data.
- You use GetSendQuota and GetSendStatistics to retrieve your sending quotas and your statistics (delivery attempts, rejects, bounces, and complaints).
You can read more about the APIs in the SES API Reference.
I'm confident that you will find SES to be easy to use and that it  will save you a lot of time and a lot of headaches as you build and  deploy your applications. As always, please feel free to leave me a  comment with your thoughts (and plans) for SES.
By the way, if you are planning to use SES, you might also want to investigate Litmus.This  AWS-powered email preview tool will let you see how your email will  look when it is rendered by 34 separate email clients and devices  including four versions of Lotus Notes and five versions of Microsoft  Outlook. Litmus runs on Amazon EC2 and stores the rendered images on Amazon S3 (read the Litmus case study for more information).
-- Jeff;
PS - There's a secret message embedded within the SES "hero graphic" on the AWS home page!  Can you figure out what it says? If you are having trouble reading it,  use your browser's zoom function (press the Control and + keys on  Firefox). If that isn't good enough for you, here's a slightly larger version of the graphic.
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